George Janossy, London, UK

CD4: a marker in time


Professor George Janossy (professor-emeritus UCL) started cellular immunology at National-Blood Centre (Budapest). Since 1970 in London he investigated lymphocyte physiology at NIMR and UCL, followed by introducing flow-cytometry for leukaemia with Melvyn Greaves and monoclonal antibodies (for MRC leukaemia trials) and transplantation (with Sandoz-Novartis). At Royal-Free minimal leukaemic disease was diagnosed (with Dario Campana) and the natural history of HIV/AIDS disease described (RF-haemophilia cohort). The flow-cytometric HIV diagnostics was transferred to resource-poor conditions with Deborah Glencross, Frank Mandy, Howard Shapiro and others.